SRM, spermidine synthase

SRM, spermidine synthase

• The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]

• Gene Synonyms (spermidine synthase, putrescine aminopropyltransferase, spermidine synthase-1, PAPT, SPDSY, SPS1, SRML1,)
• NCBI Gene ID: 6723
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P19623
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

spermidine synthase interacts with:

• 5'-nucleotidase domain containing 1
  alanyl-tRNA synthetase domain containing 1
  anterior gradient 2, protein disulphide isomerase family member
  decapping enzyme, scavenger
  DET1 and DDB1 associated 1
  dual specificity phosphatase 19
  dual specificity phosphatase 28
  EF-hand domain containing 1
  F-box protein 7
  golgi phosphoprotein 3
  limb development membrane protein 1 like
  nuclear RNA export factor 1
  pleckstrin homology domain containing A4
  PTGES3L-AARSD1 readthrough
  regulation of nuclear pre-mRNA domain containing 1B
  spermidine synthase
  telomeric repeat binding factor 1
  TOR signaling pathway regulator
  ubiquitin conjugating enzyme E2 M
  vascular cell adhesion molecule 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.