HLTF, helicase like transcription factor

HLTF, helicase like transcription factor

• This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (helicase-like transcription factor, DNA-binding protein/plasminogen activator inhibitor-1 regulator, RING finger protein 80, RING-type E3 ubiquitin transferase HLTF, SNF2-like 3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, sucrose nonfermenting protein 2-like 3, sucrose nonfermenting-like 3, HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1,)
• NCBI Gene ID: 6596
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K5B6
  UNIPROT ID#>>Q05BZ6
  UNIPROT ID#>>A0A0C4DGA6
  UNIPROT ID#>>Q14527
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

helicase like transcription factor interacts with:

• adaptor related protein complex 4 subunit sigma 1
  aprataxin and PNKP like factor
  bromodomain containing 7
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  ceramide kinase
  checkpoint with forkhead and ring finger domains
  chromodomain helicase DNA binding protein 1 like
  DDB1 and CUL4 associated factor 1
  denticleless E3 ubiquitin protein ligase homolog
  elongation factor Tu GTP binding domain containing 2
  ER membrane protein complex subunit 2
  ETAA1 activator of ATR kinase
  F-box and WD repeat domain containing 11
  golgi to ER traffic protein 4
  H2A clustered histone 4
  H2B clustered histone 1
  H4 clustered histone 1
  helicase like transcription factor
  Nanog homeobox
  nuclear factor of activated T cells 5
  nuclear receptor subfamily 2 group C member 2
  peptidase, mitochondrial processing subunit alpha
  pleckstrin homology domain containing A4
  RAD18 E3 ubiquitin protein ligase
  RAN binding protein 2
  ring finger protein 146
  ring finger protein 166
  RNA polymerase II associated protein 1
  SNF2 histone linker PHD RING helicase
  SNF2 histone linker PHD RING helicase
  SNW domain containing 1
  Sp1 transcription factor
  Sp3 transcription factor
  SprT-like N-terminal domain
  structural maintenance of chromosomes 1A
  sulfotransferase family 1C member 2
  synaptopodin
  transcription elongation factor A like 4
  transcription factor 7 like 2
  ubiquitin C
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 V2
  ubiquitin conjugating enzyme E2 Z
  ubiquitin specific peptidase 7
  WD repeat domain 76
  WW domain binding protein 4
  zinc finger and BTB domain containing 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.