POLR2D, RNA polymerase II subunit D

POLR2D, RNA polymerase II subunit D

• This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II 16 kDa polypeptide, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16 kDa subunit, RNA polymerase II subunit B4, RNA polymerase II subunit hsRBP4, RNA polymerase II subunit hsRPB4, polymerase (RNA) II (DNA directed) polypeptide D, polymerase (RNA) II subunit D, HSRBP4, HSRPB4, RBP4, RPB16, RPB4,)
• NCBI Gene ID: 5433
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15514
  UNIPROT ID#>>A0A024RAJ4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA polymerase II subunit D interacts with:

• actin related protein 1A
  activating transcription factor 7 interacting protein
  activating transcription factor 7 interacting protein
  ankyrin repeat and SOCS box containing 6
  cellular communication network factor 6
  copine 2
  CTR9 homolog, Paf1/RNA polymerase II complex component
  cullin 5
  dynactin subunit 2
  elongator acetyltransferase complex subunit 2
  elongin A
  GPN-loop GTPase 3
  H4 clustered histone 1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  integrator complex subunit 10
  integrator complex subunit 3
  integrator complex subunit 5
  integrator complex subunit 6
  mediator complex subunit 1
  mediator complex subunit 10
  mediator complex subunit 19
  mediator complex subunit 21
  mediator complex subunit 26
  mediator complex subunit 28
  mediator complex subunit 29
  mediator complex subunit 9
  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
  PIH1 domain containing 1
  proteasome 20S subunit beta 9
  pseudouridine synthase 7
  RecQ like helicase 5
  regulation of nuclear pre-mRNA domain containing 1A
  regulation of nuclear pre-mRNA domain containing 1B
  regulation of nuclear pre-mRNA domain containing 1B
  RNA guanylyltransferase and 5'-phosphatase
  RNA polymerase II associated protein 2
  RNA polymerase II subunit D
  RNA polymerase II subunit G
  RNA polymerase II subunit I
  RNA polymerase II subunit J
  RNA polymerase II subunit M
  RNA polymerase II, I and III subunit E
  RNA polymerase II, I and III subunit H
  RNA polymerase II, I and III subunit K
  RNA polymerase II, I and III subunit L
  small nuclear ribonucleoprotein polypeptide A'
  SPT5 homolog, DSIF elongation factor subunit
  SRC proto-oncogene, non-receptor tyrosine kinase
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  synapse defective Rho GTPase homolog 1
  TNFAIP3 interacting protein 2
  tripartite motif containing 29
  tumor protein, translationally-controlled 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  WW domain containing E3 ubiquitin protein ligase 2
  X-ray repair cross complementing 5
  zinc finger and SCAN domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.