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HERC4, HECT and RLD domain containing E3 ubiquitin protein ligase 4

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HERC4, HECT and RLD domain containing E3 ubiquitin protein ligase 4

  • HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]

  • Gene Synonyms (probable E3 ubiquitin-protein ligase HERC4, HECT domain and RCC1-like domain-containing protein 4, HECT-type E3 ubiquitin transferase HERC4, hect domain and RLD 4,)
  • NCBI Gene ID: 26091
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A024QZN8
    UNIPROT ID#>>Q5GLZ8
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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