HERC6, HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

HERC6, HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

• HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (probable E3 ubiquitin-protein ligase HERC6, HECT domain and RCC1-like domain-containing protein 6, HECT-type E3 ubiquitin transferase HERC6, hect domain and RLD 6, potential ubiquitin ligase,)
• NCBI Gene ID: 55008
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IVU3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 interacts with:

• HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
  potassium channel tetramerization domain containing 15

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