GTF2A1L, general transcription factor IIA subunit 1 like

GTF2A1L, general transcription factor IIA subunit 1 like

• The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]

• Gene Synonyms (TFIIA-alpha and beta-like factor, GTF2A1-like factor, TFIIA large subunit isoform ALF, TFIIA-alpha/beta-like factor, general transcription factor II A, 1-like factor, general transcription factor IIA 1-like, testis secretory sperm-binding protein Li 230m, ALF,)
• NCBI Gene ID: 11036
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VKA3
  UNIPROT ID#>>Q9UNN4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

general transcription factor IIA subunit 1 like interacts with:

• achaete-scute family bHLH transcription factor 3
  MAF bZIP transcription factor F
  NK2 homeobox 3
  RNA binding fox-1 homolog 2
  T cell leukemia homeobox 3
  zinc finger and BTB domain containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.