MAFF, MAF bZIP transcription factor F

MAFF, MAF bZIP transcription factor F

• The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

• Gene Synonyms (transcription factor MafF, v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, U-MAF, hMafF,)
• NCBI Gene ID: 23764
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9ULX9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAF bZIP transcription factor F interacts with:

• basic leucine zipper ATF-like transcription factor 2
  basic leucine zipper ATF-like transcription factor 3
  BTB domain and CNC homolog 2
  calcium binding and coiled-coil domain 1
  deuterosome assembly protein 1
  GIT ArfGAP 1
  glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
  MAF bZIP transcription factor F
  MIS12 kinetochore complex component
  NIMA related kinase 9
  retrotransposon Gag like 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.