POP1, POP1 homolog, ribonuclease P/MRP subunit

POP1, POP1 homolog, ribonuclease P/MRP subunit

• This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

• Gene Synonyms (ANXD2, ribonucleases P/MRP protein subunit POP1, hPOP1, processing of precursor 1, ribonuclease P/MRP subunit, processing of precursors 1,)
• NCBI Gene ID: 10940
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99575
  UNIPROT ID#>>Q96F88
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

POP1 homolog, ribonuclease P/MRP subunit interacts with:

• 4HAUS augmin-like complex, subunit 8
  chromosome 18 open reading frame 21
  COP9 signalosome subunit 5
  cullin associated and neddylation dissociated 1
  cyclic GMP-AMP synthase
  DGCR8 microprocessor complex subunit
  dicer 1, ribonuclease III
  EBNA1 binding protein 2
  F-box protein 21
  forkhead box Q1
  G-patch domain containing 4
  GTP binding protein 4
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  HIV-1 Tat specific factor 1
  kinesin family member 2C
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  lin-28 homolog A
  methylphosphate capping enzyme
  methyltransferase like 17
  nucleolar protein interacting with the FHA domain of MKI67
  nucleolus and neural progenitor protein
  obscurin like cytoskeletal adaptor 1
  pescadillo ribosomal biogenesis factor 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  POP1 homolog, ribonuclease P/MRP subunit
  POP5 homolog, ribonuclease P/MRP subunit
  proline rich 11
  PYD and CARD domain containing
  RAD18 E3 ubiquitin protein ligase
  ribonuclease P and MRP subunit p25
  ribonuclease P/MRP subunit p21
  ribosomal RNA processing 8
  ribosome binding protein 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 123
  RIO kinase 1
  RNA binding motif protein 34
  RNA binding motif protein 4B
  SERPINE1 mRNA binding protein 1
  signal recognition particle 72
  sirtuin 1
  sirtuin 7
  splicing factor 3a subunit 3
  striatin interacting protein 1
  vir like m6A methyltransferase associated
  Y box protein 1
  zinc finger and BTB domain containing 38
  zinc finger CCCH-type containing 3
  zinc finger protein 622
  zinc finger protein 692
  zinc finger protein 71

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.