GloResponse™ NFAT-RE-luc2P HEK293 Cell Line Technical Bulletin

Instructions for Use of Product(s)
Literature # TB363

The GloResponse™ NFAT-RE-luc2P HEK293 Cell Line is a clonal derivative of Human Embryonic Kidney 293 (HEK293) cells. These cells contain a luciferase gene (luc2P) under the control of a minimal TATA promoter with multiple Nuclear Factor of Activated T-cell response elements (NFAT-REs). NFAT-REs are the DNA-binding sequences for the NFAT family of transcription factors, which are responsible for regulating a variety of biological functions including cell proliferation, cytokine production, and cardiovascular development. The GloResponse™ NFAT-RE-luc2P HEK293 Cell Line is designed for rapid and convenient analysis of any cellular response that results in modulation of NFAT activities.

Summary of Changes
The following changes were made to the 2/16 revision of this document:
1. The patent information was updated to remove expired statements.
2. The document design was updated.

Printed in USA. Revised 2/16.