KDM4A, lysine demethylase 4A

KDM4A, lysine demethylase 4A

• This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]

• Gene Synonyms (lysine-specific demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, jmjC domain-containing histone demethylation protein 3A, jumonji C domain-containing histone demethylase 3A, jumonji domain containing 2, jumonji domain containing 2A, jumonji domain-containing protein 2A, lysine (K)-specific demethylase 4A, tudor domain containing 14A, JHDM3A, JMJD2, JMJD2A, TDRD14A,)
• NCBI Gene ID: 9682
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75164
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine demethylase 4A interacts with:

• abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
  F-box and leucine rich repeat protein 4
  F-box protein 22
  lysine demethylase 4A
  lysine demethylase 4B
  lysine demethylase 4C
  nuclear RNA export factor 1
  protein arginine methyltransferase 5
  ring finger protein 168
  vir like m6A methyltransferase associated
  WD repeat domain 48
  zinc finger protein 414

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.