ATP6V1G1, ATPase H+ transporting V1 subunit G1

ATP6V1G1, ATPase H+ transporting V1 subunit G1

• This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (V-type proton ATPase subunit G 1, ATPase, H+ transporting, lysosomal (vacuolar proton pump), member J, ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1, V-ATPase 13 kDa subunit 1, V-ATPase subunit G 1, vacuolar ATP synthase subunit M16, vacuolar H(+)-ATPase subunit G 1, vacuolar proton pump subunit G 1, vacuolar proton pump subunit M16, ATP6G, ATP6G1, ATP6GL, ATP6J, Vma10,)
• NCBI Gene ID: 9550
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75348
  UNIPROT ID#>>A0A024R883
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase H+ transporting V1 subunit G1 interacts with:

• ATPase H+ transporting accessory protein 2
  ATPase H+ transporting V1 subunit C2
  ATPase H+ transporting V1 subunit D
  ATPase H+ transporting V1 subunit E2
  BCL2 like 11
  BTB domain containing 9
  coactivator associated arginine methyltransferase 1
  component of oligomeric golgi complex 3
  cytidine monophosphate N-acetylneuraminic acid synthetase
  golgi reassembly stacking protein 2
  golgi transport 1B
  golgin A6 family like 9
  kelch like family member 18
  laccase domain containing 1
  LDOC1 regulator of NFKB signaling
  membrane bound transcription factor peptidase, site 2
  N-terminal glutamine amidase 1
  nuclear distribution C, dynein complex regulator
  pleckstrin homology domain containing A4
  regulator of microtubule dynamics 3
  small glutamine rich tetratricopeptide repeat containing beta
  solute carrier family 35 member A1
  spastin
  transmembrane protein 63B
  ubiquitin like modifier activating enzyme 2
  vacuolar protein sorting 28
  vacuolar protein sorting 4B
  WD repeat domain 7
  zinc finger protein 511

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.