SLC4A8, solute carrier family 4 member 8

SLC4A8, solute carrier family 4 member 8

• The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Gene Synonyms (electroneutral sodium bicarbonate exchanger 1, electroneutral Na(+)-driven Cl-HCO3 exchanger, k-NBC3, solute carrier family 4, sodium bicarbonate cotransporter, member 8, NBC3, NDCBE,)
• NCBI Gene ID: 9498
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q2Y0W8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 4 member 8 interacts with:

• aarF domain containing kinase 2
  ATP binding cassette subfamily C member 4
  ATPase cation transporting 13A2
  autophagy related 9A
  chromosome 1 open reading frame 43
  ER membrane protein complex subunit 3
  ER membrane protein complex subunit 7
  G protein-coupled receptor 89B
  GH3 domain containing
  lysocardiolipin acyltransferase 1
  OMA1 zinc metallopeptidase
  pecanex 3
  solute carrier family 12 member 6
  sorting nexin 14
  suppression of tumorigenicity 7 like
  thioredoxin related transmembrane protein 2
  transmembrane protein 63A
  transmembrane protein 63B
  UL16 binding protein 2
  UPF3B regulator of nonsense mediated mRNA decay

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.