TNFRSF14, TNF receptor superfamily member 14

TNFRSF14, TNF receptor superfamily member 14

• This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Gene Synonyms (tumor necrosis factor receptor superfamily member 14, CD40-like protein, herpes virus entry mediator A, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), tumor necrosis factor receptor-like gene2, ATAR, CD270, HVEA, HVEM, LIGHTR, TR2,)
• NCBI Gene ID: 8764
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R052
  UNIPROT ID#>>Q92956
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF receptor superfamily member 14 interacts with:

• B and T lymphocyte associated
  CD160 molecule
  centrosomal protein 126
  DR1 associated protein 1
  GCN1 activator of EIF2AK4
  histone deacetylase 3
  histone deacetylase 4
  integrin alpha FG-GAP repeat containing 1
  protein disulfide isomerase family A member 6
  SEC11 homolog A, signal peptidase complex subunit
  TNF receptor superfamily member 14
  ubiquilin 4
  UDP-glucose glycoprotein glucosyltransferase 1
  WD repeat domain 73

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.