BHLHE40, basic helix-loop-helix family member e40

BHLHE40, basic helix-loop-helix family member e40

• This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]

• Gene Synonyms (class E basic helix-loop-helix protein 40, basic helix-loop-helix domain containing, class B, 2, class B basic helix-loop-helix protein 2, differentially expressed in chondrocytes 1, differentially expressed in chondrocytes protein 1, differentiated embryo chondrocyte expressed gene 1, enhancer-of-split and hairy-related protein 2, stimulated by retinoic acid gene 13 protein, BHLHB2, Clast5, DEC1, HLHB2, SHARP-2, SHARP2, STRA13, Stra14,)
• NCBI Gene ID: 8553
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6IB83
  UNIPROT ID#>>O14503
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

basic helix-loop-helix family member e40 interacts with:

• aph-1 homolog A, gamma-secretase subunit
  basic helix-loop-helix family member e40
  basic helix-loop-helix family member e41
  beta-transducin repeat containing E3 ubiquitin protein ligase
  bromodomain containing 7
  cyclin K
  cysteine rich DPF motif domain containing 1
  DAZ associated protein 2
  family with sequence similarity 83 member A
  F-box and WD repeat domain containing 11
  G protein signaling modulator 1
  germ cell-less 2, spermatogenesis associated
  heterogeneous nuclear ribonucleoprotein L like
  kelch domain containing 7B
  keratin associated protein 1-3
  keratin associated protein 19-1
  keratin associated protein 19-5
  keratin associated protein 19-7
  keratin associated protein 23-1
  keratin associated protein 6-1
  keratin associated protein 6-2
  keratin associated protein 8-1
  La ribonucleoprotein 4
  LIM domain only 3
  MAGE family member D1
  microspherule protein 1
  N-alpha-acetyltransferase 50, NatE catalytic subunit
  NIMA related kinase 6
  nucleolar complex associated 4 homolog
  NUMB like endocytic adaptor protein
  pleckstrin homology domain containing B2
  POU class 6 homeobox 2
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  RAD54 like 2
  ras homolog family member J
  Rho related BTB domain containing 3
  RNA binding fox-1 homolog 1
  RNA binding motif protein 23
  RNA binding protein, mRNA processing factor
  RNA binding protein, mRNA processing factor 2
  serine/threonine kinase 19
  SET and MYND domain containing 1
  SET domain bifurcated histone lysine methyltransferase 1
  SIN3 transcription regulator family member A
  small ArfGAP2
  suppressor of glucose, autophagy associated 1
  terminal nucleotidyltransferase 5A
  terminal nucleotidyltransferase 5B
  tetratricopeptide repeat domain 23
  thioredoxin like 4B
  TNFAIP3 interacting protein 2
  toll interacting protein
  transducer of ERBB2, 2
  ubiquitin specific peptidase 21
  ubiquitin specific peptidase 54
  VAC14 component of PIKFYVE complex
  VENT homeobox
  vir like m6A methyltransferase associated
  zinc fingers and homeoboxes 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.