TTF2, transcription termination factor 2

TTF2, transcription termination factor 2

• This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription termination factor 2, F2, RNA polymerase II termination factor, human factor 2, lodestar homolog, lodestar protein, transcription release factor 2, transcription termination factor, RNA polymerase II, zinc finger, GRF-type containing 6, HuF2, ZGRF6,)
• NCBI Gene ID: 8458
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0F1
  UNIPROT ID#>>Q9UNY4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription termination factor 2 interacts with:

• BICD cargo adaptor 2
  bromodomain containing 7
  caseinolytic mitochondrial matrix peptidase chaperone subunit B
  centriolin
  centrobin, centriole duplication and spindle assembly protein
  centrosomal protein 120
  centrosomal protein 128
  centrosomal protein 152
  centrosomal protein 162
  COBW domain containing 1
  copper metabolism domain containing 1
  cyclin dependent kinase like 3
  decapping mRNA 1A
  dickkopf WNT signaling pathway inhibitor 3
  DR1 associated protein 1
  family with sequence similarity 131 member B
  forkhead box P1
  glucocorticoid modulatory element binding protein 2
  hepatitis A virus cellular receptor 2
  histone deacetylase 11
  histone deacetylase 7
  histone H4 transcription factor
  interleukin 17 receptor A
  IQ motif containing F1
  kinesin family member 4A
  limb development membrane protein 1 like
  matrin 3
  ninein
  ninein like
  peroxiredoxin 4
  pleckstrin homology domain containing A4
  programmed cell death 6 interacting protein
  proteasome (prosome, macropain) subunit, beta type 5
  protein phosphatase 6 regulatory subunit 1
  RAB, member of RAS oncogene family like 2A
  RAB2B, member RAS oncogene family
  sirtuin 3
  src kinase associated phosphoprotein 1
  TNFAIP3 interacting protein 1
  transforming acidic coiled-coil containing protein 3
  tripartite motif containing 28
  vir like m6A methyltransferase associated
  zinc finger and SCAN domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.