PTP4A1, protein tyrosine phosphatase 4A1

PTP4A1, protein tyrosine phosphatase 4A1

• This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]

• Gene Synonyms (protein tyrosine phosphatase type IVA 1, PVT1/PTP4A1 fusion, phosphatase of regenerating liver 1, protein tyrosine phosphatase type IVA protein 1, protein tyrosine phosphatase type IVA, member 1, protein-tyrosine phosphatase of regenerating liver 1, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1,)
• NCBI Gene ID: 7803
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q93096
  UNIPROT ID#>>A0A024R8J2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein tyrosine phosphatase 4A1 interacts with:

• activating transcription factor 7
  acyl-CoA thioesterase 8
  aminopeptidase puromycin sensitive
  cAMP responsive element binding protein 3 like 2
  centrosomal protein 55
  cms1 ribosomal small subunit homolog
  COPI coat complex subunit gamma 1
  copine 3
  cyclin and CBS domain divalent metal cation transport mediator 1
  cyclin and CBS domain divalent metal cation transport mediator 2
  cyclin and CBS domain divalent metal cation transport mediator 3
  cyclin and CBS domain divalent metal cation transport mediator 4
  DNA polymerase delta interacting protein 2
  eukaryotic translation initiation factor 3 subunit L
  eukaryotic translation initiation factor 3 subunit M
  F-box protein 22
  flavin adenine dinucleotide synthetase 1
  FMR1 autosomal homolog 1
  GADD45G interacting protein 1
  guanine monophosphate synthase
  kinesin family member 21B
  leucine rich repeat containing 39
  leucine rich repeat kinase 2
  metallo-beta-lactamase domain containing 2
  mitochondrial ribosomal protein S28
  mono-ADP ribosylhydrolase 1
  MRT4 homolog, ribosome maturation factor
  nucleolar protein interacting with the FHA domain of MKI67
  nudix hydrolase 12
  nudix hydrolase 16
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  protein tyrosine phosphatase 4A1
  protein tyrosine phosphatase 4A2
  ribosomal protein S19 binding protein 1
  staphylococcal nuclease and tudor domain containing 1
  thioredoxin domain containing 5
  TNF alpha induced protein 8
  transient receptor potential cation channel subfamily C member 4 associated protein
  tubulin alpha 1b
  ubiquitin specific peptidase 11
  zinc finger protein 212

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.