XPNPEP1, X-prolyl aminopeptidase 1

XPNPEP1, X-prolyl aminopeptidase 1

• This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]

• Gene Synonyms (xaa-Pro aminopeptidase 1, X-Pro aminopeptidase 1, X-prolyl aminopeptidase (aminopeptidase P) 1, soluble, X-prolyl aminopeptidase 1, soluble, aminoacylproline aminopeptidase, aminopeptidase P, cytosolic, cytosolic aminopeptidase P, soluble aminopeptidase P, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1,)
• NCBI Gene ID: 7511
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5T6H7
  UNIPROT ID#>>Q9NQW7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

X-prolyl aminopeptidase 1 interacts with:

• ankyrin repeat and SOCS box containing 6
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inhibitor 5
  ATPase H+ transporting V1 subunit D
  BAG cochaperone 3
  cytokine induced apoptosis inhibitor 1
  dCTP pyrophosphatase 1
  dimethylglycine dehydrogenase
  DISC1 scaffold protein
  DNA polymerase alpha 2, accessory subunit
  dual specificity phosphatase 26
  EH domain containing 1
  FKBP prolyl isomerase 9
  general transcription factor IIIC subunit 4
  glucosamine-6-phosphate deaminase 1
  golgi reassembly stacking protein 2
  H2A.Z variant histone 2
  immunity related GTPase Q
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
  MYG1 exonuclease
  myotubularin related protein 2
  N-acetylglucosamine kinase
  nuclear RNA export factor 1
  nuclear transport factor 2
  nucleolar protein 3
  nudix hydrolase 3
  phosphodiesterase 12
  phospholipase A2 activating protein
  poly(U) binding splicing factor 60
  RAB30, member RAS oncogene family
  RAD50 interactor 1
  ring finger protein 20
  ring finger protein 40
  serine/threonine kinase 39
  spindlin family member 2B
  TAR DNA binding protein
  TOR signaling pathway regulator
  tripartite motif containing 25
  ubiquitin C-terminal hydrolase L5
  ubiquitin like modifier activating enzyme 6
  vesicle trafficking 1
  WD repeat domain 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.