WIPF1, WAS/WASL interacting protein family member 1

WIPF1, WAS/WASL interacting protein family member 1

• This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (WAS/WASL-interacting protein family member 1, WASP-interacting protein, Wiskott-Aldrich syndrome protein interacting protein, protein PRPL-2, testicular tissue protein Li 226, PRPL-2, WAS2, WASPIP, WIP,)
• NCBI Gene ID: 7456
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VJZ9
  UNIPROT ID#>>O43516
  UNIPROT ID#>>Q2YDC4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WAS/WASL interacting protein family member 1 interacts with:

• abl interactor 2
  BAG cochaperone 3
  calcium voltage-gated channel auxiliary subunit gamma 2
  Fas activated serine/threonine kinase
  gigaxonin
  homer scaffold protein 3
  intersectin 2
  NCK adaptor protein 2
  pre-mRNA processing factor 40 homolog A
  proline-serine-threonine phosphatase interacting protein 1
  protein kinase C and casein kinase substrate in neurons 1
  protein kinase C and casein kinase substrate in neurons 2
  protein kinase C and casein kinase substrate in neurons 3
  retention in endoplasmic reticulum sorting receptor 1
  SEC24 homolog C, COPII coat complex component
  SH3 domain containing kinase binding protein 1
  SH3 domain containing ring finger 1
  SLIT-ROBO Rho GTPase activating protein 2
  WASP like actin nucleation promoting factor
  WW domain binding protein 4
  WW domain containing E3 ubiquitin protein ligase 2
  zeta chain of T cell receptor associated protein kinase 70

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.