RYR2, ryanodine receptor 2

RYR2, ryanodine receptor 2

• This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ryanodine receptor 2, cardiac muscle ryanodine receptor-calcium release channel, cardiac-type ryanodine receptor, islet-type ryanodine receptor, kidney-type ryanodine receptor, ryanodine receptor 2 (cardiac), type 2 ryanodine receptor, ARVC2, ARVD2, RYR-2, RyR, VTSIP,)
• NCBI Gene ID: 6262
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92736
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ryanodine receptor 2 interacts with:

• A-kinase anchoring protein 6
  homer scaffold protein 1
  ryanodine receptor 2
  ryanodine receptor 3
  sorcin
  syntrophin alpha 1
  telomeric repeat binding factor 1
  telomeric repeat binding factor 2
  tripartite motif containing 25

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.