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ARHGEF26, Rho guanine nucleotide exchange factor 26

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ARHGEF26, Rho guanine nucleotide exchange factor 26

  • This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

  • Gene Synonyms (rho guanine nucleotide exchange factor 26, Rho guanine nucleotide exchange factor (GEF) 26, SH3 domain-containing guanine exchange factor, Src homology 3 domain-containing guanine nucleotide exchange factor, testicular tissue protein Li 171, CSGEF, HMFN1864, SGEF,)
  • NCBI Gene ID: 26084
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A140VJU4
    UNIPROT ID#>>B3KXG0
    UNIPROT ID#>>Q96DR7
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho guanine nucleotide exchange factor 26 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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