DARS2, aspartyl-tRNA synthetase 2, mitochondrial

DARS2, aspartyl-tRNA synthetase 2, mitochondrial

• The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009]

• Gene Synonyms (aspartate--tRNA ligase, mitochondrial, aspartate tRNA ligase 2, mitochondrial, aspartyl-tRNA synthetase, mitochondrial, ASPRS, LBSL, MT-ASPRS, mtAspRS,)
• NCBI Gene ID: 55157
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8Z9
  UNIPROT ID#>>Q9H9J7
  UNIPROT ID#>>Q6PI48
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aspartyl-tRNA synthetase 2, mitochondrial interacts with:

• asparaginyl-tRNA synthetase 2, mitochondrial
  decapping mRNA 2
  developmental pluripotency-associated 3
  dihydropyrimidinase like 5
  forkhead box I2
  limb development membrane protein 1 like
  mitochondrial rRNA methyltransferase 1
  pleckstrin homology domain containing A4
  ring finger protein 123
  synoviolin 1
  tetraspanin 33
  thrombospondin type 1 domain containing 7B
  transmembrane protein 239
  zinc finger containing ubiquitin peptidase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.