NARS2, asparaginyl-tRNA synthetase 2, mitochondrial

NARS2, asparaginyl-tRNA synthetase 2, mitochondrial

• This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]

• Gene Synonyms (probable asparagine--tRNA ligase, mitochondrial, asparagine tRNA ligase 2, mitochondrial (putative), asparaginyl-tRNA synthetase 2, mitochondrial (putative), deafness, autosomal recessive 94, probable asparaginyl-tRNA synthetase, mitochondrial, DFNB94, SLM5, asnRS,)
• NCBI Gene ID: 79731
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KPX5
  UNIPROT ID#>>Q96I59
  UNIPROT ID#>>Q9H5H1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

asparaginyl-tRNA synthetase 2, mitochondrial interacts with:

• glutamyl-tRNA amidotransferase subunit C
  NADH:ubiquinone oxidoreductase core subunit S7
  oxidoreductase like domain containing 1
  solute carrier family 25 member 41

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.