GCA, grancalcin

GCA, grancalcin

• This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Aug 2016]

• Gene Synonyms (grancalcin, grancalcin, EF-hand calcium-binding protein, grancalcin, penta-EF-hand protein, GCL,)
• NCBI Gene ID: 25801
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z322
  UNIPROT ID#>>H7BXD5
  UNIPROT ID#>>P28676
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

grancalcin interacts with:

• abhydrolase domain containing 11
  BPI fold containing family A member 1
  chromosome 11 open reading frame 49
  F-box and leucine rich repeat protein 5
  glutathione S-transferase omega 2
  grancalcin
  neuraminidase 4
  parvin alpha
  RNA binding fox-1 homolog 1
  SIGLEC family like 1
  stathmin 4
  synaptophysin like 2
  transmembrane protein 255A
  yippee like 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.