BPIFA1, BPI fold containing family A member 1

BPIFA1, BPI fold containing family A member 1

• This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]

• Gene Synonyms (BPI fold-containing family A member 1, ligand-binding protein RYA3, lung-specific protein X, nasopharyngeal carcinoma-related protein, palate lung and nasal epithelium clone protein, palate, lung and nasal epithelium associated, protein Plunc, secretory protein in upper respiratory tracts, short PLUNC1, tracheal epithelium enriched protein, von Ebner protein Hl, LUNX, NASG, PLUNC, SPLUNC1, SPURT, bA49G10.5,)
• NCBI Gene ID: 51297
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NP55
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BPI fold containing family A member 1 interacts with:

• alkB homolog 4, lysine demethylase
  BPI fold containing family B member 3
  citrate synthase lysine methyltransferase
  DEAD-box helicase 31
  dual specificity phosphatase 21
  FA core complex associated protein 20
  family with sequence similarity 222 member B
  GADD45G interacting protein 1
  heat shock transcription factor Y-linked 1
  heat shock transcription factor Y-linked 2
  IKBKB interacting protein
  inhibitor of CDK, cyclin A1 interacting protein 1
  interactor of little elongation complex ELL subunit 2
  INTS3 and NABP interacting protein
  ligand of numb-protein X 1
  mitochondrial translational initiation factor 3
  NHL repeat containing 2
  nucleoporin 54
  penta-EF-hand domain containing 1
  proline rich 35
  receptor transporter protein 5 (putative)
  RNA guanine-7 methyltransferase activating subunit
  small nuclear ribonucleoprotein U11/U12 subunit 25
  sorting nexin 27
  sterile alpha motif domain containing 11
  TEPSIN adaptor related protein complex 4 accessory protein
  tet methylcytosine dioxygenase 2
  transmembrane protein 237
  ubiquilin 4
  vacuolar protein sorting 25 homolog
  zinc finger protein 765

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.