ETHE1, ETHE1 persulfide dioxygenase

ETHE1, ETHE1 persulfide dioxygenase

• This gene encodes a member of the metallo beta-lactamase family of iron-containing proteins involved in the mitochondrial sulfide oxidation pathway. The encoded protein catalyzes the oxidation of a persulfide substrate to sulfite. Certain mutations in this gene cause ethylmalonic encephalopathy, an infantile metabolic disorder affecting the brain, gastrointestinal tract and peripheral vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

• Gene Synonyms (persulfide dioxygenase ETHE1, mitochondrial, ethylmalonic encephalopathy 1, hepatoma subtracted clone one protein, protein ETHE1, mitochondrial, sulfur dioxygenase ETHE1, HSCO, YF13H12,)
• NCBI Gene ID: 23474
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5N8
  UNIPROT ID#>>A0A0S2Z580
  UNIPROT ID#>>O95571
  UNIPROT ID#>>B2RCZ7
  UNIPROT ID#>>A0A0S2Z5B3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ETHE1 persulfide dioxygenase interacts with:

• ATPase H+ transporting V1 subunit H
  autophagy related 9A
  chloride intracellular channel 4
  cytochrome c oxidase assembly factor 7 (putative)
  ETHE1 persulfide dioxygenase
  ferredoxin 2
  glutaredoxin 5
  golgi reassembly stacking protein 2
  immunoglobin superfamily member 21
  keratin associated protein 19-2
  ligand dependent nuclear receptor interacting factor 1
  NADH:ubiquinone oxidoreductase core subunit S7
  nitrilase family member 2
  protein O-glucosyltransferase 3
  thioredoxin 2
  tyrosyl-tRNA synthetase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.