GLRX5, glutaredoxin 5

GLRX5, glutaredoxin 5

• This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010]

• Gene Synonyms (glutaredoxin-related protein 5, mitochondrial, epididymis secretory sperm binding protein, glutaredoxin 5 homolog, monothiol glutaredoxin-5, C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA, SIDBA3, SPAHGC,)
• NCBI Gene ID: 51218
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86SX6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutaredoxin 5 interacts with:

• bolA family member 3
  CDGSH iron sulfur domain 3
  chromosome 1 open reading frame 198
  chromosome 15 open reading frame 48
  coenzyme Q9
  coiled-coil-helix-coiled-coil-helix domain containing 10
  cytidine/uridine monophosphate kinase 1
  elaC ribonuclease Z 2
  histidine triad nucleotide binding protein 2
  iron-sulfur cluster assembly 2
  methionine sulfoxide reductase B3
  mitochondrial rRNA methyltransferase 1
  myotrophin
  spermatogenesis associated 20
  succinate dehydrogenase complex assembly factor 3
  succinate dehydrogenase complex assembly factor 4
  tRNA methyltransferase 61B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.