CILK1, ciliogenesis associated kinase 1

CILK1, ciliogenesis associated kinase 1

• Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ECO, EJM10, ICK, LCK2, MRK, hICK, serine/threonine-protein kinase ICK, MAK-related kinase, iciliogenesis associated kinase 1, intestinal cell (MAK-like) kinase, intestinal cell kinase, laryngeal cancer kinase 2, serine/threonine protein kinase,)
• NCBI Gene ID: 22858
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RD59
  UNIPROT ID#>>Q9UPZ9
  UNIPROT ID#>>B3KQG4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ciliogenesis associated kinase 1 interacts with:

• alpha 1,4-galactosyltransferase (P blood group)
  alpha-1,4-N-acetylglucosaminyltransferase
  centromere protein L
  cleavage and polyadenylation specific factor 1
  clusterin associated protein 1
  cyclin dependent kinase 20
  DEP domain containing 1
  family with sequence similarity 217 member B
  F-box protein 7
  intraflagellar transport 172
  katanin interacting protein
  La ribonucleoprotein 7, transcriptional regulator
  LSM family member 14B
  musashi RNA binding protein 2
  ninein
  nucleoporin 188
  regulatory associated protein of MTOR complex 1
  SET and MYND domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.