PRMT3, protein arginine methyltransferase 3

PRMT3, protein arginine methyltransferase 3

• This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Gene Synonyms (protein arginine N-methyltransferase 3, HMT1 hnRNP methyltransferase-like 3, heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3, HRMT1L3,)
• NCBI Gene ID: 10196
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0A0MSN7
  UNIPROT ID#>>Q8WUV3
  UNIPROT ID#>>O60678
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein arginine methyltransferase 3 interacts with:

• ADP ribosylation factor interacting protein 1
  BEN domain containing 7
  centrobin, centriole duplication and spindle assembly protein
  egl-9 family hypoxia inducible factor 3
  exportin 7
  Fas associated factor 1
  GDP-mannose pyrophosphorylase B
  heat shock protein family H (Hsp110) member 1
  kelch like family member 10
  PIH1 domain containing 2
  pleckstrin homology domain containing A4
  programmed cell death 2 like
  RAN binding protein 2
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  Sec23 homolog A, COPII coat complex component
  syntaxin 19
  testis specific serine kinase substrate
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.