WASF2, WASP family member 2

WASF2, WASP family member 2

• This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

• Gene Synonyms (wiskott-Aldrich syndrome protein family member 2, WAS protein family member 2, WASP family Verprolin-homologous protein 2, WASP family protein member 2, WASP family protein member 4, protein WAVE-2, putative Wiskott-Aldrich syndrome protein family member 4, suppressor of cyclic-AMP receptor (WASP-family), verprolin homology domain-containing protein 2, IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2,)
• NCBI Gene ID: 10163
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6W5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WASP family member 2 interacts with:

• ABI family member 3
  archaelysin family metallopeptidase 1
  autophagy related 16 like 1
  BAR/IMD domain containing adaptor protein 2
  BICD cargo adaptor 2
  Cbl proto-oncogene C
  centrosomal protein 19
  coiled-coil domain containing 27
  cytoplasmic FMR1 interacting protein 1
  cytoplasmic FMR1 interacting protein 2
  Enah/Vasp-like
  gap junction protein beta 7
  general transcription factor II E, polypeptide 2 (beta subunit)
  hook microtubule tethering protein 3
  intersectin 2
  Kruppel like factor 16
  LIM homeobox 4
  NCK associated protein 1
  NHS like 2
  potassium channel tetramerization domain containing 10
  pre-mRNA processing factor 40 homolog A
  protein kinase C and casein kinase substrate in neurons 1
  transcription elongation regulator 1
  translocase of inner mitochondrial membrane 50
  transmembrane protein 17
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  vir like m6A methyltransferase associated
  WASH complex subunit 3
  WASP family member 2
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 511

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.