CELA1, chymotrypsin like elastase 1

CELA1, chymotrypsin like elastase 1

• Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]

• Gene Synonyms (ELA1, chymotrypsin-like elastase family member 1, chymotrypsin like elastase family member 1, elastase 1, pancreatic, elastase-1, pancreatic elastase 1,)
• NCBI Gene ID: 1990
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNI1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chymotrypsin like elastase 1 interacts with:

• BCL6 corepressor
  centrosomal protein 164
  chaperonin containing TCP1 subunit 2
  DISC1 scaffold protein
  eukaryotic translation initiation factor 4E family member 2
  GLI family zinc finger 3
  helicase with zinc finger
  histone deacetylase 3
  KRAB-A domain containing 1
  lipoprotein(a)
  peptidase inhibitor 3
  proline rich 14
  proline rich coiled-coil 2A
  serpin family A member 1
  SET and MYND domain containing 2
  signal induced proliferation associated 1 like 2
  tubulin beta 1 class VI
  ubiquitin specific peptidase 54
  zinc finger protein 318

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.