BNIP3, BCL2 interacting protein 3

BNIP3, BCL2 interacting protein 3

• This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]

• Gene Synonyms (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BCL2/adenovirus E1B 19kDa interacting protein 3, BCL2/adenovirus E1B interacting protein 3, nineteen kD interacting protein-3, NIP3,)
• NCBI Gene ID: 664
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6NVY4
  UNIPROT ID#>>Q12983
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BCL2 interacting protein 3 interacts with:

• adhesion molecule with Ig like domain 1
  ADP ribosylation factor like GTPase 13B
  BAG cochaperone 3
  BCL2 interacting protein 3
  BCL2 interacting protein 3 like
  cAMP responsive element binding protein 3
  cAMP responsive element binding protein 3 like 1
  CD3e molecule
  CD47 molecule
  CKLF like MARVEL transmembrane domain containing 5
  claudin 9
  CLN8 transmembrane ER and ERGIC protein
  C-type lectin domain containing 7A
  EBP cholestenol delta-isomerase
  ELOVL fatty acid elongase 4
  ERGIC and golgi 3
  estrogen receptor 2
  estrogen receptor binding site associated antigen 9
  family with sequence similarity 209 member A
  family with sequence similarity 241 member B
  fetal and adult testis expressed 1
  free fatty acid receptor 2
  FXYD6-FXYD2 readthrough
  G protein-coupled receptor 152
  G protein-coupled receptor 42
  glutamyl aminopeptidase
  hepsin
  histone deacetylase 1
  HIVEP zinc finger 1
  hypoxia inducible factor 1 subunit alpha
  interferon gamma receptor 2
  jagunal homolog 1
  kinectin 1
  lamin A/C
  low density lipoprotein receptor class A domain containing 1
  major facilitator superfamily domain containing 14B
  mal, T cell differentiation protein like
  membrane spanning 4-domains A3
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 beta
  nuclear cap binding protein subunit 1
  OPA1 mitochondrial dynamin like GTPase
  parkin RBR E3 ubiquitin protein ligase
  protein phosphatase 4 regulatory subunit 3B
  protein phosphatase targeting COQ7
  proteolipid protein 2
  PTEN induced kinase 1
  Ras homolog, mTORC1 binding
  receptor accessory protein 2
  reprimo, TP53 dependent G2 arrest mediator homolog
  ribonuclease K
  ring finger protein 24
  SEC22 homolog A, vesicle trafficking protein
  Sec23 homolog A, COPII coat complex component
  sequestosome 1
  small integral membrane protein 3
  sodium voltage-gated channel beta subunit 3
  solute carrier family 31 member 2
  solute carrier family 35 member B1
  solute carrier family 6 member 17
  sperm acrosome associated 1
  tenomodulin
  thioredoxin related transmembrane protein 2
  TLC domain containing 4
  transglutaminase 2
  transmembrane 4 L six family member 18
  transmembrane protein 101
  transmembrane protein 106C
  transmembrane protein 11
  transmembrane protein 205
  transmembrane protein 30A
  transmembrane serine protease 2
  zinc finger DHHC-type palmitoyltransferase 15

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.