CD47, CD47 molecule

CD47, CD47 molecule

• This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

• Gene Synonyms (leukocyte surface antigen CD47, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, Rh-related antigen, antigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, integrin associated protein, integrin-associated signal transducer, IAP, MER6, OA3,)
• NCBI Gene ID: 961
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0A1TSG4
  UNIPROT ID#>>Q08722
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD47 molecule interacts with:

• BSCL2 lipid droplet biogenesis associated, seipin
  ELAV like RNA binding protein 1
  erythrocyte membrane protein band 4.2
  G protein subunit alpha i1
  G protein subunit alpha q
  G protein subunit beta 3
  galectin 8
  galectin 9
  galectin 9C
  GNAS complex locus
  inositol-pentakisphosphate 2-kinase
  integrin subunit alpha V
  integrin subunit beta 1
  killer cell lectin like receptor G2
  leukocyte immunoglobulin like receptor B4
  lysophosphatidic acid receptor 1
  mitochondrial translational initiation factor 3
  mucin 1, cell surface associated
  protein tyrosine kinase 2
  purinergic receptor P2Y2
  PVR cell adhesion molecule
  reticulophagy regulator family member 3
  Rh associated glycoprotein
  ring finger protein 4
  signal regulatory protein alpha
  solute carrier family 1 member 5
  spectrin repeat containing nuclear envelope family member 4
  sphingosine-1-phosphate receptor 1
  testis expressed 101
  tetraspanin 5
  thrombospondin 1
  transmembrane 4 L six family member 18
  transmembrane protein 128
  transmembrane protein 167B
  ubiquilin 1
  WASP family member 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.