We believe this site might serve you best:

United States

English Continue

This country code will remain if no action is taken to change it.

Don't see your country?
Promega Corporation

ADCC Bioassay Effector Cells, Propagation Model Technical Manual

  • Instructions for Use of Product(s)
  • G7102

Literature # TM385

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruction by components of the cellmediated immune system, such as natural killer cells. The ADCC Reporter Bioassay is a bioluminescent reporter assay for quantifying biological activity on pathway activation by therapeutic antibody drugs in an ADCC mechanism of action (MOA) assay. The ADCC Reporter Bioassay can be performed with the ADCC Bioassay Effector Cells, Propagation Model, described here, a model that allows cell banking and propagation under a unique purchase agreement. The assay combines a simple, add-mixread format and an optimized protocol to provide a bioassay that has low variability and high accuracy. These performance characteristics make the bioassay suitable for application across antibody drug research, development and manufactured lot release.

Revised 9/13

 

PDF Icon Complete Protocol PDF (1438kb)

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.

Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

Ask us! We are here to help you.