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Promega Corporation

HPK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human HPK1 (1–346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. HPK1 or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. HPK1 is also known as mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1). HPK1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway (1). HPK1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76 (2).

ADP-Glo™ Kinase Assay is a...

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Product Size Conc. Catalog # *List Price Order QTY Add to Cart
HPK1 Kinase Enzyme System
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HPK1 Kinase Enzyme System  Components

10μg
- V4098 $ 406.00 Add to cart

HPK1 Kinase Enzyme System

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HPK1 Kinase Enzyme System

 Components

1mg
- V6398 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + HPK1 Kinase Enzyme System
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ADP-Glo™ Kinase Assay + HPK1 Kinase Enzyme System  Components

  • HPK1 Kinase Enzyme System

    V40981 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4099 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V4098, V6398, V4099 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V4099 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V4099 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V4099 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V4099 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V4099 U.S. Pat. No. 8,183,007 and other patents pending.

V4099 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V4099 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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