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Promega Corporation

HPK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human HPK1 (1–346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. HPK1 or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. HPK1 is also known as mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1). HPK1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway (1). HPK1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76 (2).

ADP-Glo™ Kinase Assay is a...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart
HPK1 Kinase Enzyme System 10μg
- V4098 $ 406.00 Add to cart

HPK1 Kinase Enzyme System

1mg
- V6398 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + HPK1 Kinase Enzyme System 1 each
- V4099 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

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