CASP8AP2, caspase 8 associated protein 2

CASP8AP2, caspase 8 associated protein 2

• This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]

• Gene Synonyms (CASP8-associated protein 2, FLASH homolog RIP25, FLICE associated huge, FLICE-associated huge protein, human FLASH, CED-4, FLASH, RIP25,)
• NCBI Gene ID: 9994
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKL3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

caspase 8 associated protein 2 interacts with:

• 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  caspase 8 associated protein 2
  centrosomal protein 135
  short coiled-coil protein
  TNFAIP3 interacting protein 2
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.