NOS1AP, nitric oxide synthase 1 adaptor protein

NOS1AP, nitric oxide synthase 1 adaptor protein

• This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009]

• Gene Synonyms (carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON), C-terminal PDZ ligand of neuronal nitric oxide synthase protein, ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain, nitric oxide synthase 1 (neuronal) adaptor protein, 6330408P19Rik, CAPON,)
• NCBI Gene ID: 9722
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75052
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nitric oxide synthase 1 adaptor protein interacts with:

• AKNA domain containing 1
  anaphase promoting complex subunit 2
  CaM kinase like vesicle associated
  cancer/testis antigen family 45 member A5
  DEAD-box helicase 41
  ELL associated factor 1
  family with sequence similarity 133 member A
  G protein-coupled receptor 156
  kinesin light chain 3
  NFKB activating protein
  NHP2 ribonucleoprotein
  NKAP domain containing 1
  nuclear assembly factor 1 ribonucleoprotein
  Opa interacting protein 5
  ras related dexamethasone induced 1
  regulator of hemoglobinization and erythroid cell expansion
  RING1 and YY1 binding protein
  RNA binding protein with serine rich domain 1
  SREK1 interacting protein 1
  transient receptor potential cation channel subfamily C member 4 associated protein
  translocase of outer mitochondrial membrane 40
  vir like m6A methyltransferase associated
  zinc finger CCHC-type containing 17

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.