FHL5, four and a half LIM domains 5

FHL5, four and a half LIM domains 5

• The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Apr 2016]

• Gene Synonyms (four and a half LIM domains protein 5, LIM protein ACT, activator of cAMP-responsive element modulator (CREM) in testis, activator of cAMP-responsive element modulator in testis, 1700027G07Rik, ACT, FHL-5, dJ393D12.2,)
• NCBI Gene ID: 9457
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5TD97
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

four and a half LIM domains 5 interacts with:

• abl interactor 2
  ADAMTS like 5
  ankyrin repeat and sterile alpha motif domain containing 1A
  ankyrin repeat domain 55
  BCL2 binding component 3
  BCL6B transcription repressor
  BTG3 associated nuclear protein
  cation channel sperm associated 1
  cell division cycle 20B
  centrosomal protein 76
  cyclin and CBS domain divalent metal cation transport mediator 3
  cytosolic thiouridylase subunit 1
  deltex E3 ubiquitin ligase 2
  DLG associated protein 4
  doublecortin domain containing 2B
  doublesex and mab-3 related transcription factor 3
  dynein axonemal light chain 4
  family with sequence similarity 214 member B
  family with sequence similarity 71 member C
  FEZ family zinc finger 1
  four and a half LIM domains 4
  four and a half LIM domains 5
  glutamine rich 1
  hes related family bHLH transcription factor with YRPW motif 2
  highly divergent homeobox
  homeobox A1
  hyaluronan and proteoglycan link protein 2
  inositol hexakisphosphate kinase 3
  kinesin family member 17
  leucine rich repeat containing 41
  mago homolog B, exon junction complex subunit
  mitotic spindle positioning
  myozenin 3
  neural proliferation, differentiation and control 1
  NIMA related kinase 6
  nuclear FMR1 interacting protein 2
  phenylalanyl-tRNA synthetase 2, mitochondrial
  pleckstrin homology domain containing A2
  pleckstrin homology domain containing N1
  protein phosphatase 1 regulatory subunit 18
  protein phosphatase 1 regulatory subunit 32
  RAB26, member RAS oncogene family
  SEC31 homolog A, COPII coat complex component
  shiftless antiviral inhibitor of ribosomal frameshifting
  sodium channel modifier 1
  sprouty RTK signaling antagonist 1
  stabilizer of axonemal microtubules 1
  thioredoxin 2
  tumor suppressor 2, mitochondrial calcium regulator
  yippee like 3
  zinc finger and BTB domain containing 33
  zinc finger HIT-type containing 1
  zinc finger MYM-type containing 1
  zinc finger protein 250
  zinc finger protein 251
  zinc finger protein 408
  zinc finger protein 417
  zinc finger protein 440
  zinc finger protein 446
  zinc finger protein 564
  zinc finger protein 581
  zinc finger protein 587
  zinc finger protein 613
  zinc finger protein 688
  zinc finger protein 764
  zinc finger protein 766
  zinc finger protein 792

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.