SH2D2A, SH2 domain containing 2A

SH2D2A, SH2 domain containing 2A

• This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

• Gene Synonyms (SH2 domain-containing protein 2A, SH2 domain protein 2A, T cell specific adapter protein TSAd, T lymphocyte specific adaptor protein, VEGF receptor-associated protein, F2771, SCAP, TSAD, VRAP,)
• NCBI Gene ID: 9047
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NP31
  UNIPROT ID#>>Q5UBZ3
  UNIPROT ID#>>Q5UBZ2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SH2 domain containing 2A interacts with:

• adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  ankyrin repeat and SOCS box containing 3
  AT-rich interaction domain 5A
  DDB1 and CUL4 associated factor 12 like 1
  leucine rich repeat kinase 1
  ligand of numb-protein X 1
  LRR binding FLII interacting protein 1
  lysine demethylase 1B
  malignant fibrous histiocytoma amplified sequence 1
  mitogen-activated protein kinase kinase kinase 2
  N-alpha-acetyltransferase 16, NatA auxiliary subunit
  pleckstrin homology domain containing B1
  protein phosphatase 1 regulatory subunit 21
  pseudopodium enriched atypical kinase 1
  RAD54 homolog B
  ring finger protein 123
  terminal nucleotidyltransferase 5A
  terminal nucleotidyltransferase 5B
  zinc finger and SCAN domain containing 1
  zinc fingers and homeoboxes 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.