DGAT1, diacylglycerol O-acyltransferase 1

DGAT1, diacylglycerol O-acyltransferase 1

• This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013]

• Gene Synonyms (diacylglycerol O-acyltransferase 1, ACAT related gene product 1, acyl coenzyme A:cholesterol acyltransferase related gene 1, acyl-CoA retinol O-fatty-acyltransferase, acyl-CoA:diacylglycerol acyltransferase, diacylglycerol O-acyltransferase homolog, diglyceride acyltransferase, ARAT, ARGP1, DGAT, DIAR7,)
• NCBI Gene ID: 8694
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75907
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

diacylglycerol O-acyltransferase 1 interacts with:

• diacylglycerol O-acyltransferase 1
  protein O-mannose kinase
  tectonic family member 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.