COX4I2, cytochrome c oxidase subunit 4I2

COX4I2, cytochrome c oxidase subunit 4I2

• Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cytochrome c oxidase subunit 4 isoform 2, mitochondrial, COX IV-2, cytochrome c oxidase subunit IV isoform 2 (lung), cytochrome c oxidase subunit IV-like 2, COX4, COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2,)
• NCBI Gene ID: 84701
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96KJ9
  UNIPROT ID#>>H6SG14
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cytochrome c oxidase subunit 4I2 interacts with:

• cytochrome c oxidase subunit 4I2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.