SLX4, SLX4 structure-specific endonuclease subunit

SLX4, SLX4 structure-specific endonuclease subunit

• This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found in patients with Fanconi anemia. [provided by RefSeq, Sep 2016]

• Gene Synonyms (structure-specific endonuclease subunit SLX4, BTB/POZ domain-containing protein 12, BTBD12, FANCP, MUS312,)
• NCBI Gene ID: 84464
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IY92
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SLX4 structure-specific endonuclease subunit interacts with:

• egl-9 family hypoxia inducible factor 3
  essential meiotic structure-specific endonuclease 1
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  SLX1 homolog A, structure-specific endonuclease subunit
  SLX4 interacting protein
  SLX4 structure-specific endonuclease subunit
  ubiquitin specific peptidase 45

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.