IFT88, intraflagellar transport 88

IFT88, intraflagellar transport 88

• This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017]

• Gene Synonyms (intraflagellar transport protein 88 homolog, TPR repeat protein 10, intraflagellar transport 88 homolog, polaris homolog, probe hTg737 (polycystic kidney disease, autosomal recessive), recessive polycystic kidney disease protein Tg737 homolog, testicular tissue protein Li 93, tetratricopeptide repeat domain 10, tetratricopeptide repeat protein 10, D13S1056E, DAF19, TG737, TTC10, hTg737,)
• NCBI Gene ID: 8100
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VJL7
  UNIPROT ID#>>B3KX42
  UNIPROT ID#>>Q13099
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

intraflagellar transport 88 interacts with:

• calpain 7
  CDKN2A interacting protein
  centrosomal protein 164
  centrosomal protein 43
  ciliogenesis associated kinase 1
  clusterin associated protein 1
  coiled-coil domain containing 120
  coiled-coil domain containing 151
  cyclin-dependent kinase 1
  DENN/MADD domain containing 6A
  EMAP like 2
  eukaryotic elongation factor 2 lysine methyltransferase
  F-box protein 7
  heat shock protein family B (small) member 11
  intraflagellar transport 172
  intraflagellar transport 20
  intraflagellar transport 22
  intraflagellar transport 27
  intraflagellar transport 46
  intraflagellar transport 52
  intraflagellar transport 57
  intraflagellar transport 74
  intraflagellar transport 80
  intraflagellar transport 81
  jun B proto-oncogene
  lebercilin LCA5
  methionine sulfoxide reductase B1
  myosin, heavy polypeptide 9, non-muscle
  RAB, member of RAS oncogene family like 2B
  RecQ like helicase 4
  Rho-associated coiled-coil containing protein kinase 1
  structural maintenance of chromosomes 6
  tetratricopeptide repeat domain 26
  tetratricopeptide repeat domain 30A
  tetratricopeptide repeat domain 30B
  TRAF3 interacting protein 1
  transmembrane p24 trafficking protein 10
  tubulin, alpha 3A
  UBX domain protein 10
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.