NPL, N-acetylneuraminate pyruvate lyase

NPL, N-acetylneuraminate pyruvate lyase

• This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

• Gene Synonyms (N-acetylneuraminate lyase, N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase), N-acetylneuraminic acid aldolase, NALase, dihydrodipicolinate synthetase homolog 1, sialate-pyruvate lyase, sialic acid aldolase, C112, C1orf13, NAL, NPL1,)
• NCBI Gene ID: 80896
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BXD5
  UNIPROT ID#>>A0A087WZ70
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

N-acetylneuraminate pyruvate lyase interacts with:

• DDB1 and CUL4 associated factor 15
  N-acetylneuraminate pyruvate lyase

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