GALNT12, polypeptide N-acetylgalactosaminyltransferase 12

GALNT12, polypeptide N-acetylgalactosaminyltransferase 12

• This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.[provided by RefSeq, Mar 2011]

• Gene Synonyms (polypeptide N-acetylgalactosaminyltransferase 12, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12), colorectal cancer, susceptibility to 1, polypeptide GalNAc transferase 12, pp-GaNTase 12, protein-UDP acetylgalactosaminyltransferase 12, CRCS1, GalNAc-T12,)
• NCBI Gene ID: 79695
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IXK2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

polypeptide N-acetylgalactosaminyltransferase 12 interacts with:

• ADAM metallopeptidase domain 33
  glycoprotein integral membrane 1
  LY6/PLAUR domain containing 4
  odontogenesis associated phosphoprotein
  PARN like, ribonuclease domain containing 1
  PILR alpha associated neural protein
  tectonic family member 2
  transmembrane protein 25
  transmembrane serine protease 11B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.