BIRC7, baculoviral IAP repeat containing 7

BIRC7, baculoviral IAP repeat containing 7

• This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]

• Gene Synonyms (baculoviral IAP repeat-containing protein 7, RING finger protein 50, RING-type E3 ubiquitin transferase BIRC7, kidney inhibitor of apoptosis protein, livin inhibitor of apoptosis, melanoma inhibitor of apoptosis protein, KIAP, LIVIN, ML-IAP, MLIAP, RNF50,)
• NCBI Gene ID: 79444
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96CA5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

baculoviral IAP repeat containing 7 interacts with:

• baculoviral IAP repeat containing 7
  bolA family member 2
  bolA family member 2B
  family with sequence similarity 124 member B
  ligand dependent nuclear receptor corepressor
  proline rich 35
  TEPSIN adaptor related protein complex 4 accessory protein
  testis specific 10 interacting protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.