TSHR, thyroid stimulating hormone receptor

TSHR, thyroid stimulating hormone receptor

• The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

• Gene Synonyms (thyrotropin receptor, TSH receptor, seven transmembrane helix receptor, thyrotropin receptor-I, hTSHR-I, CHNG1, LGR3, hTSHR-I,)
• NCBI Gene ID: 7253
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P16473
  UNIPROT ID#>>A0A0A0MTJ0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thyroid stimulating hormone receptor interacts with:

• BORA aurora kinase A activator
  COBW domain containing 1
  F-box protein 7
  G protein subunit alpha 13
  IQ motif containing GTPase activating protein 2
  molybdenum cofactor sulfurase
  POTE ankyrin domain family member F
  Rab acceptor 1
  scribble planar cell polarity protein
  sterile alpha motif domain containing 1
  thyroid stimulating hormone receptor
  tRNA methyltransferase 44 homolog
  tubulin alpha 1a
  tubulin alpha 4a

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.