TNNC1, troponin C1, slow skeletal and cardiac type

TNNC1, troponin C1, slow skeletal and cardiac type

• Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

• Gene Synonyms (troponin C, slow skeletal and cardiac muscles, cardiac troponin C, slow twitch skeletal/cardiac muscle troponin C, troponin C type 1 (slow), CMD1Z, CMH13, TN-C, TNC, TNNC,)
• NCBI Gene ID: 7134
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FH91
  UNIPROT ID#>>P63316
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

troponin C1, slow skeletal and cardiac type interacts with:

• RNA binding motif protein 15B
  t-complex 10 like
  tripartite motif containing 63
  troponin C1, slow skeletal and cardiac type
  troponin I1, slow skeletal type
  troponin I2, fast skeletal type
  troponin I3, cardiac type
  troponin T1, slow skeletal type
  troponin T2, cardiac type
  ubiquitin conjugating enzyme E2 C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.