MARCHF7, membrane associated ring-CH-type finger 7

MARCHF7, membrane associated ring-CH-type finger 7

• MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]

• Gene Synonyms (E3 ubiquitin-protein ligase MARCHF7, E3 ubiquitin-protein ligase MARCH7, RING finger protein 177, RING-type E3 ubiquitin transferase MARCH7, RING-type E3 ubiquitin transferase MARCHF7, axotrophin, membrane associated ring finger 7, membrane-associated RING finger protein 7, membrane-associated RING-CH protein VII, membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase, AXO, AXOT, MARCH-VII, MARCH7, RNF177,)
• NCBI Gene ID: 64844
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F5H6W4
  UNIPROT ID#>>B7ZAR7
  UNIPROT ID#>>Q9H992
  UNIPROT ID#>>B7Z5K0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

membrane associated ring-CH-type finger 7 interacts with:

• egl-9 family hypoxia inducible factor 3
  exocyst complex component 8
  membrane associated ring-CH-type finger 7
  NLR family pyrin domain containing 3
  tripartite motif containing 65

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.