TRPV4, transient receptor potential cation channel subfamily V member 4

TRPV4, transient receptor potential cation channel subfamily V member 4

• This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

• Gene Synonyms (transient receptor potential cation channel subfamily V member 4, OSM9-like transient receptor potential channel 4, osm-9-like TRP channel 4, osmosensitive transient receptor potential channel 4, transient receptor potential protein 12, vanilloid receptor-like channel 2, vanilloid receptor-related osmotically activated channel, BCYM3, CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC,)
• NCBI Gene ID: 59341
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HBA0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transient receptor potential cation channel subfamily V member 4 interacts with:

• itchy E3 ubiquitin protein ligase
  transient receptor potential cation channel subfamily V member 4

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