ASIC4, acid sensing ion channel subunit family member 4

ASIC4, acid sensing ion channel subunit family member 4

• This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]

• Gene Synonyms (ACCN4, BNAC4, acid-sensing ion channel 4, acid sensing ion channel family member 4, acid-sensing (proton-gated) ion channel family member 4, amiloride-sensitive cation channel 4, pituitary, amiloride-sensitive cation channel family member 4, pituitary, brain sodium channel 4,)
• NCBI Gene ID: 55515
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96FT7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acid sensing ion channel subunit family member 4 interacts with:

• ALG12 alpha-1,6-mannosyltransferase
  ALG9 alpha-1,2-mannosyltransferase
  CDGSH iron sulfur domain 2
  divergent protein kinase domain 1A
  galactosidase beta 1 like 2
  inositol 1,4,5-trisphosphate receptor interacting protein
  mannosidase endo-alpha like
  neuropilin and tolloid like 2
  oxysterol binding protein like 8
  PDZ domain containing 8
  post-glycosylphosphatidylinositol attachment to proteins 6
  protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
  sphingosine-1-phosphate phosphatase 1
  thioredoxin domain containing 15
  transmembrane protein 231
  transmembrane protein with metallophosphoesterase domain
  uroplakin 3B like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.